Frequency:
After 8 weeks he was running around again. Full of energy wanting to play. These chews are the first ones that worked for us.
Since Jax started to struggle on walks we had to stop going. After 5 weeks on these we enjoy our big walk every week again, pain free.
Coco is getting much better. It’s been a little over 3 weeks and she’s acting a lot younger again!
Here’s some helpful guidance on using Orthopup joint chews, along with what many owners notice during the first 90 days of consistent use.
We recommend to give with food and fresh water.
Saw positive results in 4 weeks
Saw clear improvements in mobility within 90 days
*Survey conducted late 2025 (n=50)
Our chews are scientifically-formulated to support joint health. With consistent use, many owners begin to notice changes such as:
Everyday movement feeling easier
More interest in walks and play
Seeming happier day to day
Less hesitation when jumping onto furniture
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Research shows that joint issues become increasingly common as dogs age. Around 20% of adult dogs over five years old are affected, rising to approximately 80% in dogs over eight.
OrthoPup joint chews are formulated using well-studied active ingredients designed to support joint flexibility and everyday mobility.
Start supporting your dog’s joint health now to help maintain their mobility as they age.
Results from real owners
99%
Experienced improved mobility and comfort
94%
Would confidently recommend to friends and family
90%
Noticed their dog was happier overall
after taking Orthopup joint chews
*independent survey conducted 2025 (n=50)
Our joint support system works across key areas to help your dog move more freely, stay comfortable, and enjoy an active life for longer.
Our Advanced Joint Support Chews provide targeted, highly concentrated joint nutrition to help support bone integrity, joint function, and comfortable movement as your dog ages or stays active.
Our Complete Omega-3 Fish Oil supplies concentrated omega-3 fatty acids to help support skin integrity, coat condition, joint lubrication, and overall wellbeing.
Our Complete Multivitamin supplies carefully balanced vitamins and minerals that support every aspect of health by optimising the nutritional foundations required for mobility and holistic health.
Our ingredients have been widely studied and carefully chosen to work together in supporting joint comfort and mobility.
Colartix® trains the immune system to accept type II collagen and prevent cartilage degradation and bone resorption in the joint. Colartix® together with glucosamine and chondroitin have been shown to reduce pain by 57% and lameness by 53% in only 30 days. Within 5 months, Colartix® has been shown to reduce generalised pain by 62-81% and lameness by 78-90%.
Glucosamine is a naturally occurring compound that supports the maintenance of healthy cartilage within the joints. It helps nourish the cells responsible for cartilage structure and plays a role in maintaining joint cushioning and fluid balance, supporting comfortable movement and flexibility.
Methylsulfonylmethane (MSM) is a naturally occurring source of sulphur that is found in fresh foods and plays a role in supporting connective tissue health. MSM helps support normal joint function and overall mobility, contributing to comfort and flexibility in active and ageing dogs.
Green-Lipped Mussels are a nutrient-rich natural ingredient, supplying glucosamine, chondroitin, vitamins C and E, plus important antioxidants and minerals like copper, zinc, and selenium. Together, these nutrients help support healthy joints and contribute to the body’s normal inflammatory processes for comfortable, flexible movement.
Chondroitin is a naturally occurring compound found in connective tissue and commonly present in red meat. It plays an important role in supporting cartilage structure and helps maintain normal collagen and hyaluronic acid levels within the joint, contributing to cushioning and smooth movement.
Hyaluronic Acid is a naturally occurring component of joint fluid, where it helps support lubrication and smooth movement. As dogs age, natural levels may decline, so providing Hyaluronic Acid in the diet can help maintain normal joint fluid balance and support comfortable mobility.
A potent anti inflammatory, boosting antioxidant protection, aiding digestion, supporting liver function and potentially supporting cognitive/ heart health. This powerhouse also improves skin & coat health as an added benefit.
Vitamin C supports normal collagen synthesis, an essential component of healthy cartilage. It also contributes to antioxidant protection against oxidative stress and helps support the effective use of nutrients involved in joint structure and function.
Studies in dogs including a controlled trial with daily vitamin E supplementation have explored impacts on joint inflammation and clinical signs in osteoarthritis, with some research reporting reduced markers of inflammation in controlled models.
Boswellia serrata is a plant-derived extract known for its role in supporting normal inflammatory balance and joint function. As part of a comprehensive joint formula alongside Type II collagen, glucosamine and chondroitin, it contributes to the maintenance of healthy cartilage and comfortable mobility in active and ageing dogs.
Piperine has been shown in animal research to enhance the bioavailability of co-administered nutrients by modulating metabolic pathways, supporting improved absorption of key joint-support actives.
Active ingredients: Glucosamine 200mg, MSM 200mg, Green-Lipped Mussel 150mg, Chondroitin 35mg, Hyaluronic Acid 10mg, Type 2 Collagen 100mg, Turmeric 60mg, Vitamin C 30mg, Vitamin E 2mg, Boswellia Serrata 75mg, Piperine 0.5mg.
Other ingredients: Brewer's yeast, potato starch, vegetable glycerin, Potato flakes, dried apple pomace, Tapioca flour, Coconut oil, Salmon oil, Sunflower lecithin, Hydrolyzed animal protein, Sorbic acid, Tocopherol extract, Flaxseed meal
Watch Luna's 3 month transformation with OrthoPup Complete Joint Support chews. Her dog dad James shared a month-by-month view of the whole journey.
We're certain you'll love our products, that's why we offer a full refund on any supplement.
The UK's Most Advanced Joint Support
Under Strict UK Feed Laws
Batch Tested
No Artificial Colours or Flavours
GMO, Hormone & Antibiotic Free
GMP/SQF Certified
In line with MHRA VMD Guidelines
Active Ingredients per chew
Glucosamine 200mg, MSM 200mg, Green-Lipped Mussels 150mg, Chondroitin 35mg, Hyaluronic Acid 10mg, Vitamin C 30mg, Turmeric extract 60mg, Vitamin E 2mg, Piperine 0.5mg, Boswellia serrata extract 75mg, Type 2 collagen 100mg.
Inactive Ingredients
Apple Cider Vinegar, Brewer’s Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pork Spray Dried Liver, Tapioca Starch.
Use your pet’s weight to follow the directions for use.
Our Advanced chews harness the superpowers of Glucosamine, Chondroitin, Green-Lipped Mussels, Hyaluronic Acid, Type 2 collagen and MSM to drive effective and visible results Our formula helps enhance joint health and improve discomfort from normal exercise and aging, helping maintain mobility. Our amazing chews can also be given to younger pups to help promote optimum bone and joint health.
They help:
To make sure your pup is getting the absolute best, our joint chews do not contain artificial preservatives. Please store in a cool, dry place, out of direct sunlight and heat, and use within 3 months of opening.
In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Advanced Mobility support includes Pork, Fish and Brewer’s Yeast (gluten).
If your pet devours an entire tub of Advanced Mobility support, they’ll be absolutely fine as long as the tub was designed for their weight category. Adverse effects can include vomiting, diarrhea, lethargy or gastrointestinal distress. If they’ve eaten more than one tub, or are experiencing symptoms for more than 24 hours, contact your vet for guidance.
Our products are proudly made in the EU from globally sourced ingredients.
Joint supplements are important because they help support and maintain joint health, particularly in aging dogs or those with specific joint-related issues. They can also be beneficial for younger pups, especially larger dogs and breeds that are prone to joint issues.
With 1 in 5 dogs developing joint issues in their lifetime (reference), it’s very important for pet parents to look out for and recognize signs of joint discomfort. Some signs to look out for include:
These are also very common signs of other issues. If your pet exhibits one or more of these, please consult your veterinarian.
Absolutely. As long as you follow our directions for use, our joint chews should not interfere with other supplements or prescription medications.
Advanced Mobility Enhancement is suitable for pets over 12 weeks of age.
GLU/CHO Method of Action Review of studies explaining how glucosamine and chondroitin work to treat and prevent arthritis
GLU/CHO Improves OA Combination supplementation significantly improves pain, weight bearing and severity scores in 70 days
Oral GLU Supplementation Oral glucosamine reduced histological signs of osteoarthritis in 8 weeks
GLU/MSM Combination Combination significantly improves pain and swelling, more effective together than alone
MSM OA Review MSM supplementation significantly improves OA-associated pain scores
GLM & Canine Arthritis Green-lipped mussel improves pain, swelling and reduces total arthritis score in dogs
GLM & Canine OA Pain GLM increases blood Omega-3 levels and reduces OA scores over 90 days
Pain Study Green-lipped mussel reduces pain in canine models within 8 weeks
Effects of Chondroitin Supplementation on OA Clinical review showing chondroitin benefits in osteoarthritis (pp. 284–288)
Hyaluronic Acid as Support for OA Hyaluronic acid supports joint lubrication and mobility
Fish Oil & Inflammatory Markers Fish oil supplementation reduces inflammatory markers in dogs with OA
Omega-3 Improves Mobility in Dogs Omega-3 supplementation improves mobility in dogs with osteoarthritis
Omega-3 Improves Clinical Signs of OA Clinical improvements in OA symptoms observed with Omega-3 supplementation
Boswellia Specific Canine Study Canine study evaluating Boswellia serrata on joint comfort and mobility outcomes
Boswellia & UC-II Combination Review Review discussing combined Boswellia and UC-II use in joint support formulations
UC-II Combination Supplement Study Study examining UC-II used within multi-ingredient joint support supplements
UC-II Mechanism of Action Explores oral tolerance and immune pathways involved in undenatured type II collagen
UC-II Anti-Inflammatory Effects Research evaluating UC-II’s influence on inflammatory pathways linked to joint stress
UC-II Pain Reduction Study Clinical research showing reduced joint discomfort and improved mobility with UC-II
UC-II Immune Modulation Study Study examining UC-II’s role in immune response modulation related to joint tissue
UC-II Compared to Pharmaceutical Interventions Comparative analysis of UC-II supplementation versus conventional pharmacological approaches
Boswellia / UC-II / GLU / CHO / GTE Combination Study Evaluation of a multi-ingredient joint support formulation in canine models
