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Geoff K
Both our dogs started supplements a year ago. They love the taste of these ones!
Both our dogs started supplements a year ago. They love the taste of these ones!
FIGHT HIP & JOINT PAIN – RESTORE MOBILITY & COMFORT!
Orthopup Complete Hip & Joint soft chews are designed to help maintain your pet’s joint health and mobility, promoting comfort and a better quality of life - especially for aging or active dogs with joint decline.
Frequency:
Our loyal customers often report great results in the first 4 weeks, but we guarantee great results in 90 days or you'll get all of your money back.
Many owners with picky eaters prefer to crumble the supplement into their dogs meals. This has also been linked to increased absorption, and it's what we recommend.
Our joint support chews offer a comprehensive list of ingredients proven in studies around the world.
The combination of ingredients we pack into one chew work together and increase efficiacy massively compared to supplements with just a jew active ingredients.
Hyaluronic Acid as Support For Joint Issues
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Results In 90 Days
Batch Tested
Made In UK With Globally Sourced Ingredients
90 Day Money Back Guarantee
Save On Subscriptions
GMP/SQF Certified
Formulated By Pet Scientists
No Artificial Colours Or Flavours
Shipped Within 24hrs
In line with MHRA VMD guidelines
Sarah T.
✔My 10 year old Labrador was struggling to get up after rest. Within a month on Orthopup she's moving so much more freely. I genuinely didn't expect it to work this well.
Sarah T.
✔My 10 year old Labrador was struggling to get up after rest. Within a month on Orthopup she's moving so much more freely. I genuinely didn't expect it to work this well.
Sarah T.
✔My 10 year old Labrador was struggling to get up after rest. Within a month on Orthopup she's moving so much more freely. I genuinely didn't expect it to work this well.
Try Risk Free with our 90-Day Money Back Guarantee
Results in as Little as 4 Weeks!
If you're not happy after 3 months of consistent use, we'll refund you.
Supports Cartilage & Joint Health
Restores Joint Lubrication
Eases Joint Stiffness After Rest
Calms the Inflammation Cycle
Provides Building Blocks for Synovial Fluid, Cartilage and Connective Tissues
Arrives in 2-4 Days | 90-Day Money Back Guarantee
With Orthopup, your dog's ability to stay mobile, active, and comfortable is supported day by day.
First Signs
UC-II begins engaging the oral tolerance pathway
Early reduction in the immune response attacking cartilage
First signs of easier movement after rest
Early signs of more energy and willingness to move
Visible Changes
UC-II actively calming the cartilage breakdown cycle
Hyaluronic Acid restoring joint lubrication
Noticeably less stiffness getting up after rest
Owners report improved willingness to walk and play
Full Impact
All three jobs — cartilage, lubrication, comfort — supported together
Joints supported, flexibility maintained, stiffness eased
Dogs regain confidence to walk, run, and play again
Owners report visible improvement in mobility and comfort
Results may vary between individual dogs.
Glucosamine HCl
The building block of cartilage. Supports structure and cushioning.
UC-II Collagen
Calms the immune response attacking cartilage. The foundation ingredient.
MSM
Calms the immune response attacking cartilage. The foundation ingredient.
Chondroitin Sulfate
Stops joints grinding down. Keeps tissue strong and flexible.
Green-Lipped Mussel
Calms the immune response attacking cartilage. The foundation ingredient.
Hyaluronic Acid
Lubricates joints from the inside. Lose this and every step gets harder.
Boswellia Serrata
Calms the immune response attacking cartilage. The foundation ingredient.
Turmeric Extract
Calms the immune response attacking cartilage. The foundation ingredient.
Vitamin C
Calms the immune response attacking cartilage. The foundation ingredient.
Vitamin E
Calms the immune response attacking cartilage. The foundation ingredient.
Piperine
Calms the immune response attacking cartilage. The foundation ingredient.
Omega-3 Fish Oil
Calms the immune response attacking cartilage. The foundation ingredient.
Based on dogs over 35kg
Here's what fellow dog owners are reporting after 90 days of consistent use*
saw a positive impact on their dog's mobility
saw a positive impact on their dog's mobility
saw a positive impact on their dog's mobility
saw a positive impact on their dog's mobility
*Based on an independent survey conducted in 2024 (n=216)
Advanced Joint Support for Dogs. The Supplement Vets Are Talking About.
It's not just a supplement. It's a powerful daily chew that helps support mobility, flexibility, and comfort. Backed by real science, real reviews, and thousands of transformations.
Orthopup is built around UC-II — an undenatured type II collagen studied head-to-head against prescription NSAIDs in dogs. Surrounding it are hyaluronic acid, glucosamine, chondroitin, and omega-3s — every ingredient chosen to address all three joint jobs at once.
Orthopup is built around UC-II — an undenatured type II collagen studied head-to-head against prescription NSAIDs in dogs. Surrounding it are hyaluronic acid, glucosamine, chondroitin, and omega-3s — every ingredient chosen to address all three joint jobs at once.
Orthopup is built around UC-II — an undenatured type II collagen studied head-to-head against prescription NSAIDs in dogs. Surrounding it are hyaluronic acid, glucosamine, chondroitin, and omega-3s — every ingredient chosen to address all three joint jobs at once.
Orthopup is built around UC-II — an undenatured type II collagen studied head-to-head against prescription NSAIDs in dogs. Surrounding it are hyaluronic acid, glucosamine, chondroitin, and omega-3s — every ingredient chosen to address all three joint jobs at once.
Orthopup is built around UC-II — an undenatured type II collagen studied head-to-head against prescription NSAIDs in dogs. Surrounding it are hyaluronic acid, glucosamine, chondroitin, and omega-3s — every ingredient chosen to address all three joint jobs at once.
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NSAIDS
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Others
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|---|---|---|---|
| Supports Cartilage | ✅ | ❌ | ⚠️ |
| Restores Lubrication | ✅ | ❌ | ⚠️ |
| Eases Inflammation | ✅ | ✅Masks pain | ⚠️ |
| Side Effect Risk | ✅ None reported | ⚠️ Kidney, liver, gut | ✅ Minimal |
| Addresses Root Cause | ✅ | ❌ Masks only | ⚠️ Partially |
| Clinically Studied | ✅ UC-II studies | ✅ | ❌ |
| Needs Vet Prescription | ✅ No | ❌ Yes | ✅ No |
Watch Luna's 3 month transformation with OrthoPup Complete Joint Support chews. Her dog dad James shared a month-by-month view of the whole journey.
We're certain you'll love our products, that's why we offer a full refund on any supplement.
Under Strict UK Feed Laws
Batch Tested
No Artificial Colours or Flavours
GMO, Hormone & Antibiotic Free
GMP/SQF Certified
In line with MHRA VMD Guidelines
Your dog's health is too important for shortcuts. That's why every batch of our chews is made with the highest quality controls in place.
Batch Tested
Batch Tested
Batch Tested
Batch Tested
Batch Tested
Batch Tested
Active Ingredients per chew
Glucosamine 200mg, MSM 200mg, Green-Lipped Mussels 150mg, Chondroitin 35mg, Hyaluronic Acid 10mg, Vitamin C 30mg, Turmeric extract 60mg, Vitamin E 2mg, Piperine 0.5mg, Boswellia serrata extract 75mg, Type 2 collagen 100mg.
Inactive Ingredients
Apple Cider Vinegar, Brewer’s Yeast, Coconut Glycerin, Coconut Oil, Dried Whey, Honey, Mixed Tocopherols, Molasses, Pork Spray Dried Liver, Tapioca Starch.
Use your pet’s weight to follow the directions for use.
Our Advanced chews harness the superpowers of Glucosamine, Chondroitin, Green-Lipped Mussels, Hyaluronic Acid, Type 2 collagen and MSM to drive effective and visible results Our formula helps enhance joint health and improve discomfort from normal exercise and aging, helping maintain mobility. Our amazing chews can also be given to younger pups to help promote optimum bone and joint health.
They help:
To make sure your pup is getting the absolute best, our joint chews do not contain artificial preservatives. Please store in a cool, dry place, out of direct sunlight and heat, and use within 3 months of opening.
In order to look out for as many pups as possible, we formulated our chews with allergies in mind. If your pet is particularly sensitive, please note that Advanced Mobility support includes Pork, Fish and Brewer’s Yeast (gluten).
If your pet devours an entire tub of Advanced Mobility support, they’ll be absolutely fine as long as the tub was designed for their weight category. Adverse effects can include vomiting, diarrhea, lethargy or gastrointestinal distress. If they’ve eaten more than one tub, or are experiencing symptoms for more than 24 hours, contact your vet for guidance.
Our products are proudly made in the EU from globally sourced ingredients.
Joint supplements are important because they help support and maintain joint health, particularly in aging dogs or those with specific joint-related issues. They can also be beneficial for younger pups, especially larger dogs and breeds that are prone to joint issues.
With 1 in 5 dogs developing joint issues in their lifetime (reference), it’s very important for pet parents to look out for and recognize signs of joint discomfort. Some signs to look out for include:
These are also very common signs of other issues. If your pet exhibits one or more of these, please consult your veterinarian.
Absolutely. As long as you follow our directions for use, our joint chews should not interfere with other supplements or prescription medications.
Advanced Mobility Enhancement is suitable for pets over 12 weeks of age.
GLU/CHO Method of Action Review of studies explaining how glucosamine and chondroitin work to treat and prevent arthritis
GLU/CHO Improves OA Combination supplementation significantly improves pain, weight bearing and severity scores in 70 days
Oral GLU Supplementation Oral glucosamine reduced histological signs of osteoarthritis in 8 weeks
GLU/MSM Combination Combination significantly improves pain and swelling, more effective together than alone
MSM OA Review MSM supplementation significantly improves OA-associated pain scores
GLM & Canine Arthritis Green-lipped mussel improves pain, swelling and reduces total arthritis score in dogs
GLM & Canine OA Pain GLM increases blood Omega-3 levels and reduces OA scores over 90 days
Pain Study Green-lipped mussel reduces pain in canine models within 8 weeks
Effects of Chondroitin Supplementation on OA Clinical review showing chondroitin benefits in osteoarthritis (pp. 284–288)
Hyaluronic Acid as Support for OA Hyaluronic acid supports joint lubrication and mobility
Fish Oil & Inflammatory Markers Fish oil supplementation reduces inflammatory markers in dogs with OA
Omega-3 Improves Mobility in Dogs Omega-3 supplementation improves mobility in dogs with osteoarthritis
Omega-3 Improves Clinical Signs of OA Clinical improvements in OA symptoms observed with Omega-3 supplementation
Boswellia Specific Canine Study Canine study evaluating Boswellia serrata on joint comfort and mobility outcomes
Boswellia & UC-II Combination Review Review discussing combined Boswellia and UC-II use in joint support formulations
UC-II Combination Supplement Study Study examining UC-II used within multi-ingredient joint support supplements
UC-II Mechanism of Action Explores oral tolerance and immune pathways involved in undenatured type II collagen
UC-II Anti-Inflammatory Effects Research evaluating UC-II’s influence on inflammatory pathways linked to joint stress
UC-II Pain Reduction Study Clinical research showing reduced joint discomfort and improved mobility with UC-II
UC-II Immune Modulation Study Study examining UC-II’s role in immune response modulation related to joint tissue
UC-II Compared to Pharmaceutical Interventions Comparative analysis of UC-II supplementation versus conventional pharmacological approaches
Boswellia / UC-II / GLU / CHO / GTE Combination Study Evaluation of a multi-ingredient joint support formulation in canine models
